| S-KLASSE (V223) S 500 EQ Boost 4-matic (223.163) | Benzin/Elektro | 320kW / 435PS | Allrad | 2999ccm | Suchen |
| S-KLASSE (V223) S 450 EQ Boost 4-matic (223.161) | Benzin/Elektro | 270kW / 367PS | Allrad | 2999ccm | Suchen |
| S-KLASSE (V223) S 350 d (223.130) | Diesel | 210kW / 286PS | Heckantrieb | 2925ccm | Suchen |
| S-KLASSE (V223) S 350 d 4-matic (223.131) | Diesel | 210kW / 286PS | Allrad | 2925ccm | Suchen |
| S-KLASSE (V223) S 400 d 4-matic (223.133) | Diesel | 243kW / 330PS | Allrad | 2925ccm | Suchen |
| S-KLASSE (V223) S 450 EQ Boost (223.160) | Benzin/Elektro | 270kW / 367PS | Heckantrieb | 2999ccm | Suchen |
| S-KLASSE (V223) S 580 4-matic (223.176) | Benzin/Elektro | 370kW / 503PS | Allrad | 3982ccm | Suchen |
| S-KLASSE (V223) S 580 e (223.168) | Benzin/Elektro | 375kW / 510PS | Heckantrieb | 2999ccm | Suchen |
| S-KLASSE (V223) S 450 e (223.166) | Benzin/Elektro | 300kW / 408PS | Heckantrieb | 2999ccm | Suchen |
| S-KLASSE (V223) S 580 e 4-matic (223.169) | Benzin/Elektro | 375kW / 510PS | Allrad | 2999ccm | Suchen |
| S-KLASSE (V223) S 450 EQ Boost 4-matic (223.161) | Benzin/Elektro | 280kW / 381PS | Allrad | 2999ccm | Suchen |
| S-KLASSE (V223) S 500 EQ Boost 4-matic (223.163) | Benzin/Elektro | 330kW / 449PS | Allrad | 2999ccm | Suchen |
| S-KLASSE (V223) S 63 AMG Hybrid 4-matic (223.182) | Benzin/Elektro | 590kW / 802PS | Allrad | 3982ccm | Suchen |
| S-KLASSE (V223) S 350 d Mild Hybrid (223.120) | Diesel/Elektro | 230kW / 313PS | Heckantrieb | 2989ccm | Suchen |
| S-KLASSE (V223) S 350 d Mild Hybrid 4-matic (223.121) | Diesel/Elektro | 230kW / 313PS | Allrad | 2989ccm | Suchen |
| S-KLASSE (V223) S 450 d Mild Hybrid 4-matic (223.123) | Diesel/Elektro | 270kW / 367PS | Allrad | 2989ccm | Suchen |